Symbol
Name
ID

Igf1r
insulin-like growth factor I receptor
MGI:96433

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Anorexia

Horner syndrome

Lewy bodies

Spinal cord compression

Neuroblastoma

Neoplasm of the nervous system

Ataxia

Parkinsonism

Myoclonus

Irritability

Delusion

Visual hallucination

Dementia

Fluctuations in consciousness

Antalgic gait

Disease(s) Associated with IGF1R

Lewy body dementia

neuroblastoma

pancreatic cancer

Mouse Phenotypes

abnormal inner hair cell kinocilium morphology

decreased oligodendrocyte progenitor number

abnormal cochlear hair cell development

decreased cochlear hair cell number

decreased cochlear inner hair cell number

decreased cochlear outer hair cell number

abnormal cochlear hair cell stereociliary bundle morphology

abnormal cochlear inner hair cell morphology

abnormal cochlear outer hair cell morphology

decreased brain size

abnormal brainstem morphology

abnormal CNS glial cell morphology

abnormal oligodendrocyte morphology

abnormal spinal cord morphology

abnormal myelination

Availability

Mouse Genotype

Igf1r^tm1Arge/Igf1r^tm1Arge

Igf1r^tm2.1Arge/Igf1r^tm2.1Arge

Igf1r^tm1Jcbr/Igf1r^tm1Jcbr
Tg(Fabp4-cre)1Abel/? (conditional)

Igf1r^tm1Arge/Igf1r^tm2Arge
Tg(Camk2a-cre)2Szi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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